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LOCUS AB031069 2487 bp mRNA PRI 27-MAY-2000
DEFINITION Homo sapiens PCCX1 mRNA for protein containing CXXC domain 1,
complete cds.
ACCESSION AB031069
VERSION AB031069.1 GI:8100074
KEYWORDS .
SOURCE Homo sapiens embryo male lung fibroblast cell_line:HuS-L12 cDNA to
mRNA.
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Primates; Catarrhini; Hominidae; Homo.
REFERENCE 1 (sites)
AUTHORS Fujino,T., Hasegawa,M., Shibata,S., Kishimoto,T., Imai,Si. and
Takano,T.
TITLE PCCX1, a novel DNA-binding protein with PHD finger and CXXC domain,
is regulated by proteolysis
JOURNAL Biochem. Biophys. Res. Commun. 271 (2), 305-310 (2000)
MEDLINE 20261256
REFERENCE 2 (bases 1 to 2487)
AUTHORS Fujino,T., Hasegawa,M., Shibata,S., Kishimoto,T., Imai,S. and
Takano,T.
TITLE Direct Submission
JOURNAL Submitted (15-AUG-1999) to the DDBJ/EMBL/GenBank databases.
Tadahiro Fujino, Keio University School of Medicine, Department of
Microbiology; Shinanomachi 35, Shinjuku-ku, Tokyo 160-8582, Japan
(E-mail:fujino@microb.med.keio.ac.jp,
Tel:+81-3-3353-1211(ex.62692), Fax:+81-3-5360-1508)
FEATURES Location/Qualifiers
source 1..2487
/organism="Homo sapiens"
/db_xref="taxon:9606"
/sex="male"
/cell_line="HuS-L12"
/cell_type="lung fibroblast"
/dev_stage="embryo"
gene 229..2199
/gene="PCCX1"
CDS 229..2199
/gene="PCCX1"
/note="a nuclear protein carrying a PHD finger and a CXXC
domain"
/codon_start=1
/product="protein containing CXXC domain 1"
/protein_id="BAA96307.1"
/db_xref="GI:8100075"
/translation="MEGDGSDPEPPDAGEDSKSENGENAPIYCICRKPDINCFMIGCD
NCNEWFHGDCIRITEKMAKAIREWYCRECREKDPKLEIRYRHKKSRERDGNERDSSEP
RDEGGGRKRPVPDPDLQRRAGSGTGVGAMLARGSASPHKSSPQPLVATPSQHHQQQQQ
QIKRSARMCGECEACRRTEDCGHCDFCRDMKKFGGPNKIRQKCRLRQCQLRARESYKY
FPSSLSPVTPSESLPRPRRPLPTQQQPQPSQKLGRIREDEGAVASSTVKEPPEATATP
EPLSDEDLPLDPDLYQDFCAGAFDDHGLPWMSDTEESPFLDPALRKRAVKVKHVKRRE
KKSEKKKEERYKRHRQKQKHKDKWKHPERADAKDPASLPQCLGPGCVRPAQPSSKYCS
DDCGMKLAANRIYEILPQRIQQWQQSPCIAEEHGKKLLERIRREQQSARTRLQEMERR
FHELEAIILRAKQQAVREDEESNEGDSDDTDLQIFCVSCGHPINPRVALRHMERCYAK
YESQTSFGSMYPTRIEGATRLFCDVYNPQSKTYCKRLQVLCPEHSRDPKVPADEVCGC
PLVRDVFELTGDFCRLPKRQCNRHYCWEKLRRAEVDLERVRVWYKLDELFEQERNVRT
AMTNRAGLLALMLHQTIQHDPLTTDLRSSADR"
BASE COUNT 564 a 715 c 768 g 440 t
ORIGIN
1 agatggcggc gctgaggggt cttgggggct ctaggccggc cacctactgg tttgcagcgg
61 agacgacgca tggggcctgc gcaataggag tacgctgcct gggaggcgtg actagaagcg
121 gaagtagttg tgggcgcctt tgcaaccgcc tgggacgccg ccgagtggtc tgtgcaggtt
181 cgcgggtcgc tggcgggggt cgtgagggag tgcgccggga gcggagatat ggagggagat
241 ggttcagacc cagagcctcc agatgccggg gaggacagca agtccgagaa tggggagaat
301 gcgcccatct actgcatctg ccgcaaaccg gacatcaact gcttcatgat cgggtgtgac
361 aactgcaatg agtggttcca tggggactgc atccggatca ctgagaagat ggccaaggcc
421 atccgggagt ggtactgtcg ggagtgcaga gagaaagacc ccaagctaga gattcgctat
481 cggcacaaga agtcacggga gcgggatggc aatgagcggg acagcagtga gccccgggat
541 gagggtggag ggcgcaagag gcctgtccct gatccagacc tgcagcgccg ggcagggtca
601 gggacagggg ttggggccat gcttgctcgg ggctctgctt cgccccacaa atcctctccg
661 cagcccttgg tggccacacc cagccagcat caccagcagc agcagcagca gatcaaacgg
721 tcagcccgca tgtgtggtga gtgtgaggca tgtcggcgca ctgaggactg tggtcactgt
781 gatttctgtc gggacatgaa gaagttcggg ggccccaaca agatccggca gaagtgccgg
841 ctgcgccagt gccagctgcg ggcccgggaa tcgtacaagt acttcccttc ctcgctctca
901 ccagtgacgc cctcagagtc cctgccaagg ccccgccggc cactgcccac ccaacagcag
961 ccacagccat cacagaagtt agggcgcatc cgtgaagatg agggggcagt ggcgtcatca
1021 acagtcaagg agcctcctga ggctacagcc acacctgagc cactctcaga tgaggaccta
1081 cctctggatc ctgacctgta tcaggacttc tgtgcagggg cctttgatga ccatggcctg
1141 ccctggatga gcgacacaga agagtcccca ttcctggacc ccgcgctgcg gaagagggca
1201 gtgaaagtga agcatgtgaa gcgtcgggag aagaagtctg agaagaagaa ggaggagcga
1261 tacaagcggc atcggcagaa gcagaagcac aaggataaat ggaaacaccc agagagggct
1321 gatgccaagg accctgcgtc actgccccag tgcctggggc ccggctgtgt gcgccccgcc
1381 cagcccagct ccaagtattg ctcagatgac tgtggcatga agctggcagc caaccgcatc
1441 tacgagatcc tcccccagcg catccagcag tggcagcaga gcccttgcat tgctgaagag
1501 cacggcaaga agctgctcga acgcattcgc cgagagcagc agagtgcccg cactcgcctt
1561 caggaaatgg aacgccgatt ccatgagctt gaggccatca ttctacgtgc caagcagcag
1621 gctgtgcgcg aggatgagga gagcaacgag ggtgacagtg atgacacaga cctgcagatc
1681 ttctgtgttt cctgtgggca ccccatcaac ccacgtgttg ccttgcgcca catggagcgc
1741 tgctacgcca agtatgagag ccagacgtcc tttgggtcca tgtaccccac acgcattgaa
1801 ggggccacac gactcttctg tgatgtgtat aatcctcaga gcaaaacata ctgtaagcgg
1861 ctccaggtgc tgtgccccga gcactcacgg gaccccaaag tgccagctga cgaggtatgc
1921 gggtgccccc ttgtacgtga tgtctttgag ctcacgggtg acttctgccg cctgcccaag
1981 cgccagtgca atcgccatta ctgctgggag aagctgcggc gtgcggaagt ggacttggag
2041 cgcgtgcgtg tgtggtacaa gctggacgag ctgtttgagc aggagcgcaa tgtgcgcaca
2101 gccatgacaa accgcgcggg attgctggcc ctgatgctgc accagacgat ccagcacgat
2161 cccctcacta ccgacctgcg ctccagtgcc gaccgctgag cctcctggcc cggacccctt
2221 acaccctgca ttccagatgg gggagccgcc cggtgcccgt gtgtccgttc ctccactcat
2281 ctgtttctcc ggttctccct gtgcccatcc accggttgac cgcccatctg cctttatcag
2341 agggactgtc cccgtcgaca tgttcagtgc ctggtggggc tgcggagtcc actcatcctt
2401 gcctcctctc cctgggtttt gttaataaaa ttttgaagaa accaaaaaaa aaaaaaaaaa
2461 aaaaaaaaaa aaaaaaaaaa aaaaaaa
//
LOCUS XM_009873 2260 bp mRNA PRI 16-APR-2001
DEFINITION Homo sapiens matrix metalloproteinase 11 (stromelysin 3) (MMP11),
mRNA.
ACCESSION XM_009873
VERSION XM_009873.2 GI:13647850
KEYWORDS .
SOURCE human.
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Primates; Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2260)
AUTHORS NCBI Annotation Project.
TITLE Direct Submission
JOURNAL Submitted (17-APR-2001) National Center for Biotechnology
Information, NIH, Bethesda, MD 20894, USA
On Apr 16, 2001 this sequence version replaced gi:11417850.
FEATURES Location/Qualifiers
source 1..2260
/organism="Homo sapiens"
/db_xref="taxon:9606"
/chromosome="22"
gene 1..2260
/gene="MMP11"
/note="ST3; SL-3; STMY3"
/db_xref="LocusID:4320"
/db_xref="MIM:185261"
CDS 23..1489
/gene="MMP11"
/codon_start=1
/product="matrix metalloproteinase 11 preproprotein"
/protein_id="XP_009873.1"
/db_xref="GI:11417851"
/translation="MAPAAWLRSAAARALLPPMLLLLLQPPPLLARALPPDAHHLHAE
RRGPQPWHAALPSSPAPAPATQEAPRPASSLRPPRCGVPDPSDGLSARNRQKRFVLSG
GRWEKTDLTYRILRFPWQLVQEQVRQTMAEALKVWSDVTPLTFTEVHEGRADIMIDFA
RYWHGDDLPFDGPGGILAHAFFPKTHREGDVHFDYDETWTIGDDQGTDLLQVAAHEFG
HVLGLQHTTAAKALMSAFYTFRYPLSLSPDDCRGVQHLYGQPWPTVTSRTPALGPQAG
IDTNEIAPLEPDAPPDACEASFDAVSTIRGELFFFKAGFVWRLRGGQLQPGYPALASR
HWQGLPSPVDAAFEDAQGHIWFFQGAQYWVYDGEKPVLGPAPLTELGLVRFPVHAALV
WGPEKNKIYFFRGRDYWRFHPSTRRVDSPVPRRATDWRGVPSEIDAAFQDADGYAYFL
RGRLYWKFDPVKVKALEGFPRLVGPDFFGCAEPANTFL"
misc_feature 260..622
/note="Peptidase_M10; Region: Matrixin"
misc_feature 332..799
/note="ZnMc; Region: Zinc-dependent metalloprotease"
misc_feature 656..769
/note="Fragilysin; Region: Fragilysin metallopeptidase
(M10C) enterotoxin"
misc_feature 914..1045
/note="hemopexin; Region: Hemopexin"
misc_feature 914..1045
/note="HX; Region: Hemopexin-like repeats"
misc_feature 1049..1141
/note="hemopexin; Region: Hemopexin"
misc_feature 1049..1162
/note="HX; Region: Hemopexin-like repeats"
misc_feature 1181..1324
/note="HX; Region: Hemopexin-like repeats"
misc_feature 1181..1324
/note="hemopexin; Region: Hemopexin"
misc_feature 1328..1456
/note="hemopexin; Region: Hemopexin"
misc_feature 1328..1459
/note="HX; Region: Hemopexin-like repeats"
BASE COUNT 396 a 723 c 677 g 464 t
ORIGIN
1 aagcccagca gccccggggc ggatggctcc ggccgcctgg ctccgcagcg cggccgcgcg
61 cgccctcctg cccccgatgc tgctgctgct gctccagccg ccgccgctgc tggcccgggc
121 tctgccgccg gacgcccacc acctccatgc cgagaggagg gggccacagc cctggcatgc
181 agccctgccc agtagcccgg cacctgcccc tgccacgcag gaagcccccc ggcctgccag
241 cagcctcagg cctccccgct gtggcgtgcc cgacccatct gatgggctga gtgcccgcaa
301 ccgacagaag aggttcgtgc tttctggcgg gcgctgggag aagacggacc tcacctacag
361 gatccttcgg ttcccatggc agttggtgca ggagcaggtg cggcagacga tggcagaggc
421 cctaaaggta tggagcgatg tgacgccact cacctttact gaggtgcacg agggccgtgc
481 tgacatcatg atcgacttcg ccaggtactg gcatggggac gacctgccgt ttgatgggcc
541 tgggggcatc ctggcccatg ccttcttccc caagactcac cgagaagggg atgtccactt
601 cgactatgat gagacctgga ctatcgggga tgaccagggc acagacctgc tgcaggtggc
661 agcccatgaa tttggccacg tgctggggct gcagcacaca acagcagcca aggccctgat
721 gtccgccttc tacacctttc gctacccact gagtctcagc ccagatgact gcaggggcgt
781 tcaacaccta tatggccagc cctggcccac tgtcacctcc aggaccccag ccctgggccc
841 ccaggctggg atagacacca atgagattgc accgctggag ccagacgccc cgccagatgc
901 ctgtgaggcc tcctttgacg cggtctccac catccgaggc gagctctttt tcttcaaagc
961 gggctttgtg tggcgcctcc gtgggggcca gctgcagccc ggctacccag cattggcctc
1021 tcgccactgg cagggactgc ccagccctgt ggacgctgcc ttcgaggatg cccagggcca
1081 catttggttc ttccaaggtg ctcagtactg ggtgtacgac ggtgaaaagc cagtcctggg
1141 ccccgcaccc ctcaccgagc tgggcctggt gaggttcccg gtccatgctg ccttggtctg
1201 gggtcccgag aagaacaaga tctacttctt ccgaggcagg gactactggc gtttccaccc
1261 cagcacccgg cgtgtagaca gtcccgtgcc ccgcagggcc actgactgga gaggggtgcc
1321 ctctgagatc gacgctgcct tccaggatgc tgatggctat gcctacttcc tgcgcggccg
1381 cctctactgg aagtttgacc ctgtgaaggt gaaggctctg gaaggcttcc cccgtctcgt
1441 gggtcctgac ttctttggct gtgccgagcc tgccaacact ttcctctgac catggcttgg
1501 atgccctcag gggtgctgac ccctgccagg ccacgaatat caggctagag acccatggcc
1561 atctttgtgg ctgtgggcac caggcatggg actgagccca tgtctcctca gggggatggg
1621 gtggggtaca accaccatga caactgccgg gagggccacg caggtcgtgg tcacctgcca
1681 gcgactgtct cagactgggc agggaggctt tggcatgact taagaggaag ggcagtcttg
1741 ggcccgctat gcaggtcctg gcaaacctgg ctgccctgtc tccatccctg tccctcaggg
1801 tagcaccatg gcaggactgg gggaactgga gtgtccttgc tgtatccctg ttgtgaggtt
1861 ccttccaggg gctggcactg aagcaagggt gctggggccc catggccttc agccctggct
1921 gagcaactgg gctgtagggc agggccactt cctgaggtca ggtcttggta ggtgcctgca
1981 tctgtctgcc ttctggctga caatcctgga aatctgttct ccagaatcca ggccaaaaag
2041 ttcacagtca aatggggagg ggtattcttc atgcaggaga ccccaggccc tggaggctgc
2101 aacatacctc aatcctgtcc caggccggat cctcctgaag cccttttcgc agcactgcta
2161 tcctccaaag ccattgtaaa tgtgtgtaca gtgtgtataa accttcttct tctttttttt
2221 tttttaaact gaggattgtc attaaacaca gttgttttct
//
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