<![CDATA[
LOCUS AB031069 2487 bp mRNA PRI 27-MAY-2000
DEFINITION Homo sapiens PCCX1 mRNA for protein containing CXXC domain 1,
complete cds.
ACCESSION AB031069
VERSION AB031069.1 GI:8100074
KEYWORDS .
SOURCE Homo sapiens embryo male lung fibroblast cell_line:HuS-L12 cDNA to
mRNA.
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Primates; Catarrhini; Hominidae; Homo.
REFERENCE 1 (sites)
AUTHORS Fujino,T., Hasegawa,M., Shibata,S., Kishimoto,T., Imai,Si. and
Takano,T.
TITLE PCCX1, a novel DNA-binding protein with PHD finger and CXXC domain,
is regulated by proteolysis
JOURNAL Biochem. Biophys. Res. Commun. 271 (2), 305-310 (2000)
MEDLINE 20261256
REFERENCE 2 (bases 1 to 2487)
AUTHORS Fujino,T., Hasegawa,M., Shibata,S., Kishimoto,T., Imai,S. and
Takano,T.
TITLE Direct Submission
JOURNAL Submitted (15-AUG-1999) to the DDBJ/EMBL/GenBank databases.
Tadahiro Fujino, Keio University School of Medicine, Department of
Microbiology; Shinanomachi 35, Shinjuku-ku, Tokyo 160-8582, Japan
(E-mail:fujino@microb.med.keio.ac.jp,
Tel:+81-3-3353-1211(ex.62692), Fax:+81-3-5360-1508)
FEATURES Location/Qualifiers
source 1..2487
/organism="Homo sapiens"
/db_xref="taxon:9606"
/sex="male"
/cell_line="HuS-L12"
/cell_type="lung fibroblast"
/dev_stage="embryo"
gene 229..2199
/gene="PCCX1"
CDS 229..2199
/gene="PCCX1"
/note="a nuclear protein carrying a PHD finger and a CXXC
domain"
/codon_start=1
/product="protein containing CXXC domain 1"
/protein_id="BAA96307.1"
/db_xref="GI:8100075"
/translation="MEGDGSDPEPPDAGEDSKSENGENAPIYCICRKPDINCFMIGCD
NCNEWFHGDCIRITEKMAKAIREWYCRECREKDPKLEIRYRHKKSRERDGNERDSSEP
RDEGGGRKRPVPDPDLQRRAGSGTGVGAMLARGSASPHKSSPQPLVATPSQHHQQQQQ
QIKRSARMCGECEACRRTEDCGHCDFCRDMKKFGGPNKIRQKCRLRQCQLRARESYKY
FPSSLSPVTPSESLPRPRRPLPTQQQPQPSQKLGRIREDEGAVASSTVKEPPEATATP
EPLSDEDLPLDPDLYQDFCAGAFDDHGLPWMSDTEESPFLDPALRKRAVKVKHVKRRE
KKSEKKKEERYKRHRQKQKHKDKWKHPERADAKDPASLPQCLGPGCVRPAQPSSKYCS
DDCGMKLAANRIYEILPQRIQQWQQSPCIAEEHGKKLLERIRREQQSARTRLQEMERR
FHELEAIILRAKQQAVREDEESNEGDSDDTDLQIFCVSCGHPINPRVALRHMERCYAK
YESQTSFGSMYPTRIEGATRLFCDVYNPQSKTYCKRLQVLCPEHSRDPKVPADEVCGC
PLVRDVFELTGDFCRLPKRQCNRHYCWEKLRRAEVDLERVRVWYKLDELFEQERNVRT
AMTNRAGLLALMLHQTIQHDPLTTDLRSSADR"
BASE COUNT 564 a 715 c 768 g 440 t
ORIGIN
1 agatggcggc gctgaggggt cttgggggct ctaggccggc cacctactgg tttgcagcgg
61 agacgacgca tggggcctgc gcaataggag tacgctgcct gggaggcgtg actagaagcg
121 gaagtagttg tgggcgcctt tgcaaccgcc tgggacgccg ccgagtggtc tgtgcaggtt
181 cgcgggtcgc tggcgggggt cgtgagggag tgcgccggga gcggagatat ggagggagat
241 ggttcagacc cagagcctcc agatgccggg gaggacagca agtccgagaa tggggagaat
301 gcgcccatct actgcatctg ccgcaaaccg gacatcaact gcttcatgat cgggtgtgac
361 aactgcaatg agtggttcca tggggactgc atccggatca ctgagaagat ggccaaggcc
421 atccgggagt ggtactgtcg ggagtgcaga gagaaagacc ccaagctaga gattcgctat
481 cggcacaaga agtcacggga gcgggatggc aatgagcggg acagcagtga gccccgggat
541 gagggtggag ggcgcaagag gcctgtccct gatccagacc tgcagcgccg ggcagggtca
601 gggacagggg ttggggccat gcttgctcgg ggctctgctt cgccccacaa atcctctccg
661 cagcccttgg tggccacacc cagccagcat caccagcagc agcagcagca gatcaaacgg
721 tcagcccgca tgtgtggtga gtgtgaggca tgtcggcgca ctgaggactg tggtcactgt
781 gatttctgtc gggacatgaa gaagttcggg ggccccaaca agatccggca gaagtgccgg
841 ctgcgccagt gccagctgcg ggcccgggaa tcgtacaagt acttcccttc ctcgctctca
901 ccagtgacgc cctcagagtc cctgccaagg ccccgccggc cactgcccac ccaacagcag
961 ccacagccat cacagaagtt agggcgcatc cgtgaagatg agggggcagt ggcgtcatca
1021 acagtcaagg agcctcctga ggctacagcc acacctgagc cactctcaga tgaggaccta
1081 cctctggatc ctgacctgta tcaggacttc tgtgcagggg cctttgatga ccatggcctg
1141 ccctggatga gcgacacaga agagtcccca ttcctggacc ccgcgctgcg gaagagggca
1201 gtgaaagtga agcatgtgaa gcgtcgggag aagaagtctg agaagaagaa ggaggagcga
1261 tacaagcggc atcggcagaa gcagaagcac aaggataaat ggaaacaccc agagagggct
1321 gatgccaagg accctgcgtc actgccccag tgcctggggc ccggctgtgt gcgccccgcc
1381 cagcccagct ccaagtattg ctcagatgac tgtggcatga agctggcagc caaccgcatc
1441 tacgagatcc tcccccagcg catccagcag tggcagcaga gcccttgcat tgctgaagag
1501 cacggcaaga agctgctcga acgcattcgc cgagagcagc agagtgcccg cactcgcctt
1561 caggaaatgg aacgccgatt ccatgagctt gaggccatca ttctacgtgc caagcagcag
1621 gctgtgcgcg aggatgagga gagcaacgag ggtgacagtg atgacacaga cctgcagatc
1681 ttctgtgttt cctgtgggca ccccatcaac ccacgtgttg ccttgcgcca catggagcgc
1741 tgctacgcca agtatgagag ccagacgtcc tttgggtcca tgtaccccac acgcattgaa
1801 ggggccacac gactcttctg tgatgtgtat aatcctcaga gcaaaacata ctgtaagcgg
1861 ctccaggtgc tgtgccccga gcactcacgg gaccccaaag tgccagctga cgaggtatgc
1921 gggtgccccc ttgtacgtga tgtctttgag ctcacgggtg acttctgccg cctgcccaag
1981 cgccagtgca atcgccatta ctgctgggag aagctgcggc gtgcggaagt ggacttggag
2041 cgcgtgcgtg tgtggtacaa gctggacgag ctgtttgagc aggagcgcaa tgtgcgcaca
2101 gccatgacaa accgcgcggg attgctggcc ctgatgctgc accagacgat ccagcacgat
2161 cccctcacta ccgacctgcg ctccagtgcc gaccgctgag cctcctggcc cggacccctt
2221 acaccctgca ttccagatgg gggagccgcc cggtgcccgt gtgtccgttc ctccactcat
2281 ctgtttctcc ggttctccct gtgcccatcc accggttgac cgcccatctg cctttatcag
2341 agggactgtc cccgtcgaca tgttcagtgc ctggtggggc tgcggagtcc actcatcctt
2401 gcctcctctc cctgggtttt gttaataaaa ttttgaagaa accaaaaaaa aaaaaaaaaa
2461 aaaaaaaaaa aaaaaaaaaa aaaaaaa
//
LOCUS XM_009873 2260 bp mRNA PRI 16-APR-2001
DEFINITION Homo sapiens matrix metalloproteinase 11 (stromelysin 3) (MMP11),
mRNA.
ACCESSION XM_009873
VERSION XM_009873.2 GI:13647850
KEYWORDS .
SOURCE human.
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Primates; Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2260)
AUTHORS NCBI Annotation Project.
TITLE Direct Submission
JOURNAL Submitted (17-APR-2001) National Center for Biotechnology
Information, NIH, Bethesda, MD 20894, USA
On Apr 16, 2001 this sequence version replaced gi:11417850.
FEATURES Location/Qualifiers
source 1..2260
/organism="Homo sapiens"
/db_xref="taxon:9606"
/chromosome="22"
gene 1..2260
/gene="MMP11"
/note="ST3; SL-3; STMY3"
/db_xref="LocusID:4320"
/db_xref="MIM:185261"
CDS 23..1489
/gene="MMP11"
/codon_start=1
/product="matrix metalloproteinase 11 preproprotein"
/protein_id="XP_009873.1"
/db_xref="GI:11417851"
/translation="MAPAAWLRSAAARALLPPMLLLLLQPPPLLARALPPDAHHLHAE
RRGPQPWHAALPSSPAPAPATQEAPRPASSLRPPRCGVPDPSDGLSARNRQKRFVLSG
GRWEKTDLTYRILRFPWQLVQEQVRQTMAEALKVWSDVTPLTFTEVHEGRADIMIDFA
RYWHGDDLPFDGPGGILAHAFFPKTHREGDVHFDYDETWTIGDDQGTDLLQVAAHEFG
HVLGLQHTTAAKALMSAFYTFRYPLSLSPDDCRGVQHLYGQPWPTVTSRTPALGPQAG
IDTNEIAPLEPDAPPDACEASFDAVSTIRGELFFFKAGFVWRLRGGQLQPGYPALASR
HWQGLPSPVDAAFEDAQGHIWFFQGAQYWVYDGEKPVLGPAPLTELGLVRFPVHAALV
WGPEKNKIYFFRGRDYWRFHPSTRRVDSPVPRRATDWRGVPSEIDAAFQDADGYAYFL
RGRLYWKFDPVKVKALEGFPRLVGPDFFGCAEPANTFL"
misc_feature 260..622
/note="Peptidase_M10; Region: Matrixin"
misc_feature 332..799
/note="ZnMc; Region: Zinc-dependent metalloprotease"
misc_feature 656..769
/note="Fragilysin; Region: Fragilysin metallopeptidase
(M10C) enterotoxin"
misc_feature 914..1045
/note="hemopexin; Region: Hemopexin"
misc_feature 914..1045
/note="HX; Region: Hemopexin-like repeats"
misc_feature 1049..1141
/note="hemopexin; Region: Hemopexin"
misc_feature 1049..1162
/note="HX; Region: Hemopexin-like repeats"
misc_feature 1181..1324
/note="HX; Region: Hemopexin-like repeats"
misc_feature 1181..1324
/note="hemopexin; Region: Hemopexin"
misc_feature 1328..1456
/note="hemopexin; Region: Hemopexin"
misc_feature 1328..1459
/note="HX; Region: Hemopexin-like repeats"
BASE COUNT 396 a 723 c 677 g 464 t
ORIGIN
1 aagcccagca gccccggggc ggatggctcc ggccgcctgg ctccgcagcg cggccgcgcg
61 cgccctcctg cccccgatgc tgctgctgct gctccagccg ccgccgctgc tggcccgggc
121 tctgccgccg gacgcccacc acctccatgc cgagaggagg gggccacagc cctggcatgc
181 agccctgccc agtagcccgg cacctgcccc tgccacgcag gaagcccccc ggcctgccag
241 cagcctcagg cctccccgct gtggcgtgcc cgacccatct gatgggctga gtgcccgcaa
301 ccgacagaag aggttcgtgc tttctggcgg gcgctgggag aagacggacc tcacctacag
361 gatccttcgg ttcccatggc agttggtgca ggagcaggtg cggcagacga tggcagaggc
421 cctaaaggta tggagcgatg tgacgccact cacctttact gaggtgcacg agggccgtgc
481 tgacatcatg atcgacttcg ccaggtactg gcatggggac gacctgccgt ttgatgggcc
541 tgggggcatc ctggcccatg ccttcttccc caagactcac cgagaagggg atgtccactt
601 cgactatgat gagacctgga ctatcgggga tgaccagggc acagacctgc tgcaggtggc
661 agcccatgaa tttggccacg tgctggggct gcagcacaca acagcagcca aggccctgat
721 gtccgccttc tacacctttc gctacccact gagtctcagc ccagatgact gcaggggcgt
781 tcaacaccta tatggccagc cctggcccac tgtcacctcc aggaccccag ccctgggccc
841 ccaggctggg atagacacca atgagattgc accgctggag ccagacgccc cgccagatgc
901 ctgtgaggcc tcctttgacg cggtctccac catccgaggc gagctctttt tcttcaaagc
961 gggctttgtg tggcgcctcc gtgggggcca gctgcagccc ggctacccag cattggcctc
1021 tcgccactgg cagggactgc ccagccctgt ggacgctgcc ttcgaggatg cccagggcca
1081 catttggttc ttccaaggtg ctcagtactg ggtgtacgac ggtgaaaagc cagtcctggg
1141 ccccgcaccc ctcaccgagc tgggcctggt gaggttcccg gtccatgctg ccttggtctg
1201 gggtcccgag aagaacaaga tctacttctt ccgaggcagg gactactggc gtttccaccc
1261 cagcacccgg cgtgtagaca gtcccgtgcc ccgcagggcc actgactgga gaggggtgcc
1321 ctctgagatc gacgctgcct tccaggatgc tgatggctat gcctacttcc tgcgcggccg
1381 cctctactgg aagtttgacc ctgtgaaggt gaaggctctg gaaggcttcc cccgtctcgt
1441 gggtcctgac ttctttggct gtgccgagcc tgccaacact ttcctctgac catggcttgg
1501 atgccctcag gggtgctgac ccctgccagg ccacgaatat caggctagag acccatggcc
1561 atctttgtgg ctgtgggcac caggcatggg actgagccca tgtctcctca gggggatggg
1621 gtggggtaca accaccatga caactgccgg gagggccacg caggtcgtgg tcacctgcca
1681 gcgactgtct cagactgggc agggaggctt tggcatgact taagaggaag ggcagtcttg
1741 ggcccgctat gcaggtcctg gcaaacctgg ctgccctgtc tccatccctg tccctcaggg
1801 tagcaccatg gcaggactgg gggaactgga gtgtccttgc tgtatccctg ttgtgaggtt
1861 ccttccaggg gctggcactg aagcaagggt gctggggccc catggccttc agccctggct
1921 gagcaactgg gctgtagggc agggccactt cctgaggtca ggtcttggta ggtgcctgca
1981 tctgtctgcc ttctggctga caatcctgga aatctgttct ccagaatcca ggccaaaaag
2041 ttcacagtca aatggggagg ggtattcttc atgcaggaga ccccaggccc tggaggctgc
2101 aacatacctc aatcctgtcc caggccggat cctcctgaag cccttttcgc agcactgcta
2161 tcctccaaag ccattgtaaa tgtgtgtaca gtgtgtataa accttcttct tctttttttt
2221 tttttaaact gaggattgtc attaaacaca gttgttttct
//
LOCUS XM_006269 1746 bp mRNA PRI 16-APR-2001
DEFINITION Homo sapiens matrix metalloproteinase 10 (stromelysin 2) (MMP10),
mRNA.
ACCESSION XM_006269
VERSION XM_006269.3 GI:13639675
KEYWORDS .
SOURCE human.
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Primates; Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1746)
AUTHORS NCBI Annotation Project.
TITLE Direct Submission
JOURNAL Submitted (17-APR-2001) National Center for Biotechnology
Information, NIH, Bethesda, MD 20894, USA
On Apr 16, 2001 this sequence version replaced gi:12736477.
FEATURES Location/Qualifiers
source 1..1746
/organism="Homo sapiens"
/db_xref="taxon:9606"
/chromosome="11"
gene 1..1746
/gene="MMP10"
/note="SL-2; STMY2"
/db_xref="LocusID:4319"
/db_xref="MIM:185260"
CDS 23..1456
/gene="MMP10"
/codon_start=1
/product="matrix metalloproteinase 10"
/protein_id="XP_006269.2"
/db_xref="GI:13639676"
/translation="MMHLAFLVLLCLPVCSAYPLSGAAKEEDSNKDLAQQYLEKYYNL
EKDVKQFRRKDSNLIVKKIQGMQKFLGLEVTGKLDTDTLEVMRKPRCGVPDVGHFSSF
PGMPKWRKTHLTYRIVNYTPDLPRDAVDSAIEKALKVWEEVTPLTFSRLYEGEADIMI
SFAVKEHGDFYSFDGPGHSLAHAYPPGPGLYGDIHFDDDEKWTEDASGTNLFLVAAHE
LGHSLGLFHSANTEALMYPLYNSFTELAQFRLSQDDVNGIQSLYGPPPASTEEPLVPT
KSVPSGSEMPAKCDPALSFDAISTLRGEYLFFKDRYFWRRSHWNPEPEFHLISAFWPS
LPSYLDAAYEVNSRDTVFIFKVGNEFWAIRGNEVQAGYPRGIHTLGFPPTIRKIDAAV
SDKEKKKTYFFAADKYWRFDENSQSMEQGFPRLIADDFPGVEPKVDAVLQAFGFFYFF
SGSSQFEFDPNARMVTHILKSNSWLHC"
misc_feature 131..631
/note="Peptidase_M10; Region: Matrixin"
misc_feature 323..604
/note="Methionine_synt; Region: Methionine synthase"
misc_feature 332..814
/note="ZnMc; Region: Zinc-dependent metalloprotease"
misc_feature 341..703
/note="Astacin; Region: Astacin (Peptidase family M12A)"
misc_feature 662..784
/note="Fragilysin; Region: Fragilysin metallopeptidase
(M10C) enterotoxin"
misc_feature 905..1033
/note="hemopexin; Region: Hemopexin"
misc_feature 905..1033
/note="HX; Region: Hemopexin-like repeats"
misc_feature 1037..1171
/note="hemopexin; Region: Hemopexin"
misc_feature 1184..1312
/note="hemopexin; Region: Hemopexin"
misc_feature 1184..1321
/note="HX; Region: Hemopexin-like repeats"
BASE COUNT 486 a 360 c 401 g 499 t
ORIGIN
1 aaagaaggta agggcagtga gaatgatgca tcttgcattc cttgtgctgt tgtgtctgcc
61 agtctgctct gcctatcctc tgagtggggc agcaaaagag gaggactcca acaaggatct
121 tgcccagcaa tacctagaaa agtactacaa cctcgaaaag gatgtgaaac agtttagaag
181 aaaggacagt aatctcattg ttaaaaaaat ccaaggaatg cagaagttcc ttgggttgga
241 ggtgacaggg aagctagaca ctgacactct ggaggtgatg cgcaagccca ggtgtggagt
301 tcctgacgtt ggtcacttca gctcctttcc tggcatgccg aagtggagga aaacccacct
361 tacatacagg attgtgaatt atacaccaga tttgccaaga gatgctgttg attctgccat
421 tgagaaagct ctgaaagtct gggaagaggt gactccactc acattctcca ggctgtatga
481 aggagaggct gatataatga tctcttttgc agttaaagaa catggagact tttactcttt
541 tgatggccca ggacacagtt tggctcatgc ctacccacct ggacctgggc tttatggaga
601 tattcacttt gatgatgatg aaaaatggac agaagatgca tcaggcacca atttattcct
661 cgttgctgct catgaacttg gccactccct ggggctcttt cactcagcca acactgaagc
721 tttgatgtac ccactctaca actcattcac agagctcgcc cagttccgcc tttcgcaaga
781 tgatgtgaat ggcattcagt ctctctacgg acctccccct gcctctactg aggaacccct
841 ggtgcccaca aaatctgttc cttcgggatc tgagatgcca gccaagtgtg atcctgcttt
901 gtccttcgat gccatcagca ctctgagggg agaatatctg ttctttaaag acagatattt
961 ttggcgaaga tcccactgga accctgaacc tgaatttcat ttgatttctg cattttggcc
1021 ctctcttcca tcatatttgg atgctgcata tgaagttaac agcagggaca ccgtttttat
1081 ttttaaagta ggaaatgagt tctgggccat cagaggaaat gaggtacaag caggttatcc
1141 aagaggcatc cataccctgg gttttcctcc aaccataagg aaaattgatg cagctgtttc
1201 tgacaaggaa aagaagaaaa catacttctt tgcagcggac aaatactgga gatttgatga
1261 aaatagccag tccatggagc aaggcttccc tagactaata gctgatgact ttccaggagt
1321 tgagcctaag gttgatgctg tattacaggc atttggattt ttctacttct tcagtggatc
1381 atcacagttt gagtttgacc ccaatgccag gatggtgaca cacatattaa agagtaacag
1441 ctggttacat tgctaggcga gataggggga agacagatat gggtgttttt aataaatcta
1501 ataattattc atctaatgta ttatgaggca aaatggttaa tttttcctgc atgttctgtg
1561 actgaagaag atgagccttg cagatatctg catgtgttat gaagaatgtt tctggaattc
1621 ttcacttgct tttgaattgc actgaacaga attaagaaat actcatgtgc aataggtgag
1681 agaatgtatt ttcatagatg tgttattact tcctcaataa aaagttttat tttgggcctg
1741 ttcctt
//
LOCUS XM_006271 1819 bp mRNA PRI 16-APR-2001
DEFINITION Homo sapiens matrix metalloproteinase 3 (stromelysin 1,
progelatinase) (MMP3), mRNA.
ACCESSION XM_006271
VERSION XM_006271.3 GI:13639667
KEYWORDS .
SOURCE human.
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Primates; Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1819)
AUTHORS NCBI Annotation Project.
TITLE Direct Submission
JOURNAL Submitted (17-APR-2001) National Center for Biotechnology
Information, NIH, Bethesda, MD 20894, USA
On Apr 16, 2001 this sequence version replaced gi:12736476.
FEATURES Location/Qualifiers
source 1..1819
/organism="Homo sapiens"
/db_xref="taxon:9606"
/chromosome="11"
gene 1..1819
/gene="MMP3"
/note="SL-1; STMY; STR1; STMY1"
/db_xref="LocusID:4314"
/db_xref="MIM:185250"
misc_feature 261..674
/note="Peptidase_M10; Region: Matrixin"
CDS 261..968
/gene="MMP3"
/codon_start=1
/product="matrix metalloproteinase 3 preproprotein"
/protein_id="XP_006271.2"
/db_xref="GI:13639668"
/translation="MQKFLGLEVTGKLDSDTLEVMRKPRCGVPDVGHFRTFPGIPKWR
KTHLTYRIVNYTPDLPKDAVDSAVEKALKVWEEVTPLTFSRLYEGEADIMISFAVREH
GDFYPFDGPGNVLAHAYAPGPGINGDAHFDDDEQWTKDTTGTNLFLVAAHEIGHSLGL
FHSANTEALMYPLYHSLTDLTRFRLSQDDINGIQSLYDLPLTPLRPPWYPRNLSLQNL
GRQPTVILLCPLMLSAL"
misc_feature 375..851
/note="ZnMc; Region: Zinc-dependent metalloprotease"
misc_feature 384..746
/note="Astacin; Region: Astacin (Peptidase family M12A)"
misc_feature 705..839
/note="Fragilysin; Region: Fragilysin metallopeptidase
(M10C) enterotoxin"
BASE COUNT 505 a 394 c 426 g 493 t 1 others
ORIGIN
1 acaaggaggc aggcaagaca gcaaggcata gagacaacat agagctaagt aaagccagtg
61 gaaatgaaga gtcttccaat cctactgttg ctgtgcgtgg cagtttgctc agcctatcca
121 ttggatggag ctgcaagggg tgaggacacc agcatgaacc ttgttcagaa tatctagaaa
181 actactacga cctcaaaaaa gatgtgaaac agtttgttag gagaaaggac agtggtcctg
241 ttgttaaaaa aatccgagaa atgcagaagt tccttggatt ggaggtgacg gggaagctgg
301 actccgacac tctggaggtg atgcgcaagc ccaggtgtgg agttcctgat gttggtcact
361 tcagaacctt tcctggcatc ccgaagtgga ggaaaaccca ccttacatac aggattgtga
421 attatacacc agatttgcca aaagatgctg ttgattctgc tgttgagaaa gctctgaaag
481 tctgggaaga ggtgactcca ctcacattct ccaggctgta tgaaggagag gctgatataa
541 tgatctcttt tgcagttaga gaacatggag acttttaccc ttttgatgga cctggaaatg
601 ttttggccca tgcctatgcc cctgggccag ggattaatgg agatgcccac tttgatgatg
661 atgaacaatg gacaaaggat acaacaggga ccaatttatt tctcgttgct gctcatgaaa
721 ttggccactc cctgggtctc tttcactcag ccaacactga agctttgatg tacccactct
781 atcactcact cacagacctg actcggttcc gcctgtctca agatgatata aatggcattc
841 agtccctcta tgacctcccc ctgactcccc tgagaccccc ctggtaccca cggaacctgt
901 ccctccagaa cctgggacgc cagccaactg tgatcctgct ttgtcctttg atgctgtcag
961 cactctgagg ggagaaatcc tgatctttaa agacaggcac ttttggcgca aatccctcag
1021 gaagcttgaa cctgaattgc atttgatctc ttcattttgg ccatctcttc cttcaggcgt
1081 ggatgccgca tatgaagtta ctagcaagga cctcgttttc atttttaaag ngaaatcaat
1141 tctgggctat cagaggaaat gaggtacgag ctggataccc aagaggcatc cacaccctag
1201 gtttccctcc aaccgtgagg aaaatcgatg cagccatttc tgataaggaa aagaacaaaa
1261 catatttctt tgtagaggac aaatactgga ggtgagatgc aagagaaatt ccatggagcc
1321 aggctttccc aagcaaatag ctgaagactt tccagggatt gactcaaaga ttgatgctgt
1381 ttttgaagaa tttgggttct tttatttctt tactggatct tcacagttgg agtttgaccc
1441 aaatgcaaag aaagtgacac acactttgaa gagtaacagc tggcttaatt gttgaaagag
1501 atatgtagaa ggcacaatat gggcacttta aatgaagcta ataattcttc acctaagtct
1561 ctgtgaattg aaatgttcgt tttctcctgc ctgtgctgtg actcgagtca cactcaaggg
1621 aacttgagcg tgaatctgta tcttgccggt catttttatg ttattacagg gcattcaaat
1681 gggctgctgc ttagcttgca ccttgtcaca tagagtgatc tttcccaaga gaaggggaag
1741 cactcgtgtg caacagacaa gtgactgtat ctgtgtagac tatttgctta tttaataaag
1801 acgatttgtc agttatttt
//
LOCUS NM_021964 3032 bp mRNA PRI 14-MAR-2001
DEFINITION Homo sapiens zinc finger protein 148 (pHZ-52) (ZNF148), mRNA.
ACCESSION NM_021964
VERSION NM_021964.1 GI:11415035
KEYWORDS .
SOURCE human.
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Primates; Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3032)
AUTHORS Wang Y, Kobori JA and Hood L.
TITLE The ht beta gene encodes a novel CACCC box-binding protein that
regulates T-cell receptor gene expression
JOURNAL Mol. Cell. Biol. 13 (9), 5691-5701 (1993)
MEDLINE 93361003
PUBMED 8355710
REFERENCE 2 (bases 1 to 3032)
AUTHORS Tommerup N and Vissing H.
TITLE Isolation and fine mapping of 16 novel human zinc finger-encoding
cDNAs identify putative candidate genes for developmental and
malignant disorders
JOURNAL Genomics 27 (2), 259-264 (1995)
MEDLINE 96044430
PUBMED 7557990
REFERENCE 3 (bases 1 to 3032)
AUTHORS Law DJ, Tarle SA and Merchant JL.
TITLE The human ZBP-89 homolog, located at chromosome 3q21, represses
gastrin gene expression
JOURNAL Mamm. Genome 9 (2), 165-167 (1998)
MEDLINE 98119026
PUBMED 9457682
REFERENCE 4 (bases 1 to 3032)
AUTHORS Antona V, Cammarata G, De Gregorio L, Dragani TA, Giallongo A and
Feo S.
TITLE The gene encoding the transcriptional repressor BERF-1 maps to a
region of conserved synteny on mouse chromosome 16 and human
chromosome 3 and a related pseudogene maps to mouse chromosome 8
JOURNAL Cytogenet. Cell Genet. 83 (1-2), 90-92 (1998)
MEDLINE 99126341
PUBMED 9925940
REFERENCE 5 (bases 1 to 3032)
AUTHORS Law GL, Itoh H, Law DJ, Mize GJ, Merchant JL and Morris DR.
TITLE Transcription factor ZBP-89 regulates the activity of the ornithine
decarboxylase promoter
JOURNAL J. Biol. Chem. 273 (32), 19955-19964 (1998)
MEDLINE 98352017
PUBMED 9685330
REFERENCE 6 (bases 1 to 3032)
AUTHORS Ye,S., Whatling,C., Watkins,H. and Henney,A.
TITLE Human stromelysin gene promoter activity is modulated by
transcription factor ZBP-89
JOURNAL FEBS Lett. 450 (3), 268-272 (1999)
MEDLINE 99285582
COMMENT PROVISIONAL REFSEQ: This record has not yet been subject to final
NCBI review. The reference sequence was derived from AJ236885.1.
FEATURES Location/Qualifiers
source 1..3032
/organism="Homo sapiens"
/db_xref="taxon:9606"
/chromosome="3"
/map="3q21"
/cell_line="Hela cell"
gene 1..3032
/gene="ZNF148"
/note="PHZ-52; BERF-1; ZBP-89"
/db_xref="LocusID:7707"
/db_xref="MIM:601897"
CDS 392..2776
/gene="ZNF148"
/function="transcription factor"
/note="zinc finger protein 148 (pHZ-52), BERF-1, ZBP-89"
/codon_start=1
/db_xref="LocusID:7707"
/db_xref="MIM:601897"
/product="zinc finger protein 148 (pHZ-52)"
/protein_id="NP_068799.1"
/db_xref="GI:11415036"
/translation="MNIDDKLEGLFLKCGGIDEMQSSRTMVVMGGVSGQSTVSGELQD
SVLQDRSMPHQEILAADEVLQESEMRQQDMISHDELMVHEETVKNDEEQMETHERLPQ
GLQYALNVPISVKQEITFTDVSEQLMRDKKQIREPVDLQKKKKRKQRSPAKILTINED
GSLGLKTPKSHVCEHCNAAFRTNYHLQRHVFIHTGEKPFQCSQCDMRFIQKYLLQRHE
KIHTGEKPFRCDECGMRFIQKYHMERHKRTHSGEKPYQCEYCLQYFSRTDRVLKHKRM
CHENHDKKLNTCAIKGGLLTSEEDSGFSTSPKDNSLPKKKRQKTEKKSSGMDKESALD
KSDLKKDKNDYLPVYSSSTKVKDEYMVAEYAVEMPHSSVGGSHLEDASGEIHPPKLVL
KKINSKRSLKQPLEQNQTISPLSTYEESKVSKYAFELVDKQALLDSEGNADIDQVDNL
QEGPSKPVHSSTNYDDAMQFLKKKRYLQAASNNSREYALNVGTIRSQPSVTQAAVASV
IDESTTASILESQALNVEIKSNHDKNVIPDEVLQTLLDHYSHKANGQHEISFSVADTE
VTSSISINSSEVPEVTPSENVGSSSQASSSDKANMLQEYSKFLQQALDRTSQNDAYLN
SPSLNFVTDNQTLPNQPAFSSIDKQVYATMPINSFRSGMNSPLRTTPDKSHFGLIVGD
SQHSFPFSGDETNHASATSTQDFLDQVTSQKKAEAQPVHQAYQMSSFEQPFRAPYHGS
RAGIATQFSTANGQVNLRGPGTSAEFSEFPLVNVNDNRAGMTSSPDATTGQTFG"
BASE COUNT 986 a 621 c 658 g 767 t
ORIGIN
1 gaattccgga gaaaggcgca ggggtgggag ctgttgccga agctgccaca gcaaaagttc
61 tcccccctcc ccccttcccc tcctctcaag gcccctagaa aggttggagc tgccggccct
121 gcagtcggtg accgctgacg acttcggccg cgcccgcgga tagcgggagg aatcagcagc
181 ttggaaattc aagcacgtga tctggcggga tgggcgtttg cctaacgtat ttaatggagg
241 aatcggatgg cataagtgat taaggtggta ttgaggattt ctgaagccta tgaaaggtag
301 aaactcaacc atgatttctt tttcaactct acagcattcc tttccttgaa gtcttcgttt
361 ttaccttagt ctcgggcagt tatacttaag catgaacatt gacgacaaac tggaaggatt
421 gtttcttaaa tgtggcggca tagacgaaat gcagtcttcc aggacaatgg ttgtaatggg
481 tggagtgtct ggccagtcta ctgtgtctgg agagctacag gattcagtac ttcaagatcg
541 aagtatgcct caccaggaga tccttgctgc agatgaagtg ttacaagaaa gtgaaatgag
601 acaacaggat atgatatcac atgatgaact catggtccat gaggagacag tgaaaaatga
661 tgaagagcag atggaaacac atgaaagact tcctcaagga ctacagtatg cacttaatgt
721 ccctataagc gtaaagcagg aaattacttt tactgatgta tctgagcaac tgatgagaga
781 caaaaaacaa atcagagagc cagtagactt acagaaaaag aagaagcgga aacaacgttc
841 tcccgcaaaa atccttacaa taaatgagga tggatcactt ggtttgaaaa cccctaaatc
901 tcacgtttgt gagcactgca atgctgcctt tagaacgaac tatcacttac agagacatgt
961 cttcattcat acaggtgaaa aaccatttca atgtagtcaa tgtgacatgc gtttcataca
1021 gaagtacctg cttcagagac atgagaagat tcatactggt gaaaaaccat ttcgctgtga
1081 tgaatgtggt atgagattca tacaaaaata tcatatggaa aggcataaga gaactcatag
1141 tggagaaaaa ccttaccagt gtgaatactg tttacagtat ttttccagaa cagatcgtgt
1201 attgaaacat aaacgtatgt gccatgaaaa tcatgacaaa aaactaaata catgtgccat
1261 caaaggtggc cttctgacat ctgaggaaga ttctggcttt tctacatcac caaaagacaa
1321 ctcactgcca aaaaagaaaa ggcagaaaac ggagaaaaaa tcatctggaa tggacaaaga
1381 gagtgctttg gacaaatctg acctgaaaaa agacaaaaat gattacttgc ctgtttattc
1441 ttcaagtact aaagtaaaag atgagtatat ggttgcagaa tatgctgttg aaatgccaca
1501 ttcgtcagtt gggggctcgc atttagaaga tgcgtcagga gaaatacacc cacctaagtt
1561 agttctcaaa aaaattaata gtaagagaag tctgaaacag ccactggagc aaaatcaaac
1621 aatttcacct ttatccacat atgaagagag caaagtttca aagtatgctt ttgaacttgt
1681 ggataaacag gctttactgg actcagaagg caatgctgac attgatcagg ttgataattt
1741 gcaggagggg cccagtaaac ctgtgcatag tagtactaat tatgatgatg ccatgcagtt
1801 tttgaagaag aagcggtatc ttcaagcagc aagtaacaac agcagggaat atgcgctgaa
1861 tgtgggtacc atacgttctc agccttctgt aacacaagca gctgtggcaa gtgtcattga
1921 tgaaagtacc acggcatcca tattagagtc acaggcactg aatgtggaga ttaagagtaa
1981 tcatgacaaa aatgttattc cagatgaggt actgcagact ctgttggatc attattccca
2041 caaagctaat ggacagcatg agatatcctt cagtgttgca gatactgaag tgacttctag
2101 catatcaata aattcttcag aagtaccaga ggtcacccca tcagagaatg ttggatcaag
2161 ctcccaagca tcctcatcag ataaagccaa catgttgcag gaatactcca agtttctgca
2221 gcaggctttg gacagaacta gccaaaatga tgcctatttg aatagcccga gccttaactt
2281 tgtgactgat aaccagaccc tcccaaatca gccagcattc tcttccatag acaagcaggt
2341 ctatgccacc atgcccatca atagctttcg atcaggaatg aattctccac taagaacaac
2401 tccagataag tcccactttg gactaatagt tggtgattca cagcactcat ttcccttttc
2461 aggtgatgag acaaaccatg cttctgccac atcaacacag gactttctgg atcaagtcac
2521 ttctcagaag aaagctgagg cccagcctgt ccaccaagct taccaaatga gctcctttga
2581 acagcccttc cgtgctccct atcatggatc aagagctgga atagctactc aatttagcac
2641 tgccaatgga caggtgaacc ttcggggacc agggacaagt gctgaatttt cagaatttcc
2701 cttggtgaat gtaaatgata atagagctgg gatgacatct tcacctgatg ccacaactgg
2761 ccagactttt ggctaaaaaa aaaaaaaaag tgaaataata ctggcacttt agaacagatt
2821 aatcaagagt ggggttacta tgtgtaaatg gagtgctgta cagatttaag agcaatgcgt
2881 aataacaagt taagctgata tacgatgata ataactgcat ttcgtttggt tagtcagcat
2941 tctttgaact gccttacatg ttgtcacctt tatagaagca atgcattact tgttttagat
3001 cagaaacttg ctattccacc cacaccaagt aa
//
]]>